Glucosamine Sulfate is a natural component of cartilage and synovial fluid. It is an important precursor of glycoprotein and glycosaminoglycan synthesis which play a role in the formation of hyaluronic acid and enhances the production of cartilage matrix. Glucosamine also prevents collagen degeneration in chondrocytes by inhibiting inflammatory processes, lipoxidation reactions and protein oxidation.
Chondroitin sulfate is one of the natural glycosaminoglycans composed of the alternating sugars that build the extracellular matrix of cartilage. Due to the negative charge, it is responsible for the water retention of the cartilage, which is important for pressure resistance in the joint.
Methylsulfonylmethane (MSM) is an anti-inflammatory and anti-oxidizing agent that supports the immune system by migrating the chronic deleterious effects of joint inflammation through reduction of cytokine expression.
Turmeric contains curcumin a yellow pigment with several biological actions including antioxidant, analgesic, anti-inflammatory, antiseptic activity, anticarcinogenic activity, chemopreventive, chemotherapeutic activity, anti-tumour, antiviral, antibacterial, antifungal properties and antiplatelet activity.